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Hormone Replacement Therapy in Women

Hormone Replacement Therapy in Women: What the medical literature reveals about female hormones and disease protection

This presentation is a review of some of the scientific data and studies demonstrating the beneficial effects of hormones and the health detriment that occurs when hormone levels fall.
Scientific studies support which hormones are beneficial and which hormones should be avoided. These studies are all peer-reviewed, evidence-based studies that ACOG and NAMS chose to ignore yet are of utmost importance for physicians as well as patients in determining which hormones are safe and preferable. Therefore the literature very adequately demonstrates a superiority of bioidentical hormones over their synthetic hormone counterparts, particularly when it pertains to breast cancer protection and cardiovascular protection. However, physicians must uphold the scientific standards presented in these articles in order to guarantee efficacy. Any smaller dosing than that used in medical studies, inadequate monitoring, or inappropriate, non-therapeutic serum levels of hormones may predispose one to harm due to hormone deficiency. Physicians therefore must assure adequate levels of hormones in order to assure efficacy similar to what is seen in our medical literature. Out of the many studies reviewed, no study involves the use of compounded bioidentical HRT; rather these studies utilize only pharmaceutical FDA approved bioidentical hormones in standardized doses monitored with serum testing. Emphasis will be on utilizing the same hormones at the same doses which achieve the same levels which will then attain the same results as the scientific literature supports. The best method for assuring efficacy of a treatment should be through medical studies and medical literature which is the only sensible way of establishing an evidence-based approach to our therapies.

Learning Objectives

  • Recognize benefits associated with hormones in women, and risks associated with declining hormone levels.
  • Explore scientific literature supporting hormone replacement therapy in women to protect physical and mental health as their levels decrease with age.
  • Learn how hormone replacement therapy helps women in relation to menopause, fertility, mental health, breast and ovarian cancer, cancer recurrence, cardiovascular health and gynecological endocrinology.
  • Discover how to properly use the literature to guide evidence-based hormone replacement therapy in women.

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