The last medical journal article that was presented in the last course, Treating T3 Deficiency: The Evidence You Need (Part 6), stated that exogenous hyperthyroidism (TSH suppression) with thyroid hormone administration was not associated (causative) of any adverse effect. “There is no scientific evidence that the clinical impact of TSH suppression is significant.” This meta-analysis proving no harm with thyroid hormone administration (along with TSH suppression) is in direct contrast to the opinions of the other papers/authors opinions reviewed in the last course. I reviewed many papers and opinions that TSH suppression was harmful. However, I emphasized that the studies cited were all studies that reviewed baseline TSH levels in patients with Graves’ disease. Not one study was an outcome study in patients that were prescribed/treated with thyroid hormone. However, the results of all these baseline observation studies demonstrated/proved that suppressed TSH levels (in Graves’ patients) were associated with harm, sudden cardiac death, a-fib, osteoporosis, etc. The authors of the various opinion papers went on to extrapolate that thyroid hormone administration resulting in suppressed TSH levels (biochemical hyperthyroidism) was just as bad/harmful as that seen in those studies citied in patients with Graves’ disease. Nothing could be further from the truth. That which is observed in treatment trials can be completely the opposite of what is observed in baseline observation studies. Another perfect example of ODNPC.
Controlling HgBA1C with Medications Does not Make Diabetes Disappear – It Lowers the Surrogate Marker HgBA1C
Although the pathophysiology is simple, the treatment and reversal of CVD and cancer is what is so confusing, complex, misunderstood, and ignored.
Recent Literature Supports That Low Free T3 was the Highest Independent Predictor of Death in CV Patients
If T4 Does not Improve Symptoms, and Normalizing TSH Does not Guarantee or Infer Improvement in Symptoms, Then How Should we Treat Patients?
I do not believe that there is any one subject in medicine that is as misunderstood, politicized, debated, denigrated, and contentious as thyroid hormone. The pharmaceutical thyroid industry has spent millions on brain-washing physicians and convincing them that thyroxine is the best and only thyroid medicine that should be utilized. So many patients have relayed to me that their PMD will no longer treat them if they continue to take Armour Thyroid.
Meta-Analyses of the Risks, Benefits, Complications, Adverse events, and Outcomes Associated with Testosterone Replacement
One would think that the cardiovascular and endocrine worlds would embrace this as a gamechanger for preventing both diabetes and CVD.
Testosterone replacement therapy has a significant role in protecting aging men’s health, including greater protection against heart disease, diabetes, and obesity. However, it naturally increases estrogen levels in men, which has brought the benefits of testosterone therapy into question.