Alzheimer's Disease: Potential Causes & Treatments by Krista Russ Alzheimer’s Dementia (AD) is a disease of multifactorial origin. It does not have one specific cause; rather, there are multiple pathways
LDL Cholesterol: Is It Responsible for CVD and are Statins the Solution? by Krista Russ Statins have long been the gold standard for treating high cholesterol since 1987, over thirty
As many providers can attest, Alzheimer’s Dementia (AD) is a complex brain disease that slowly destroys a person’s memory and thinking abilities until sufferers become so debilitated that they cannot carry out the simplest of tasks (1). Over six million Americans over the age of 65 suffer from dementia (1). Even grimmer, as the condition progresses, it can become fatal within as little as 3-10 years (1). Few providers would disagree with these statements. Where the tables turn is the consensus on the causes of dementia, who will get it, and whether or not dementia is a destined part of aging. Dementia is debilitating, life-altering, and ultimately, life-ending. The question is, does it have to be? Can dementia be prevented or even reversed?
Every year I struggle with the decision as to what topic would be the most appropriate for the next APIM Annual Summit. Three years ago, at Hormones & Beyond Symposium 2019, we reviewed diabetes, fasting, treatment options, and pathophysiology. Two years ago, we covered How Estrogenics are making you Fat, Sick, and Infertile. Last year, we reviewed cancer, hormones, cardiovascular disease, and prostate cancer. So, now what? Fortunately, the FDA has recently approved the first and only treatment for Alzheimer’s Disease. This was extremely political and controversial. Also recently, I attended a lecture by Dale Bredesen from U.C.L. A., a world’s expert on dementia and Alzheimer’s Disease. As a result of the foregoing, the topic for this year’s symposium was easy.
Previously, we discussed how patients are taking more medications and experiencing an endless conundrum of health issues. The systemic failure to address the root causes of disease is a huge part of the problem. Along with the proven benefits of a healthy diet, exercise, and stress management, we can greatly improve health outcomes by utilizing another evidence-based strategy: bioidentical hormone replacement therapy, or BHRT.
We continue to prescribe medicines that make IR, DM, CVD, and cancer worse, but we ignore the harm due to the therapeutic illusion that the benefits outweigh the risks. Yet we continue to ignore the plethora of data and studies demonstrating how to avoid these risks and protect against DM, CVD, and cancer.
Recently, a new cholesterol lowering drug was approved in the U.K. The press-release heralded Inclisiran, simply another PCSK-9 inhibitor, to be a game changer as it will save thousands of lives by lowering cholesterol. No, there are no outcome studies yet, only studies that demonstrate it lowers serum cholesterol 50% more than statins alone. The authors assume and extrapolate that lowering LDL cholesterol with this drug will result in thousands of lives saved. That is termed therapeutic illusion.