Why is there increased morbidity and mortality in those that don’t take ERT? This is simply because there is an increase in breast cancer recurrence in prior cancer survivors, around 350/10,000 women (that don’t take HRT). This does not mean, though, that taking estrogen increases the risk. However, those that do take BHRT do benefit from HRT despite the resistance from oncologists. The increase in breast cancer recurrence at baseline should not be extrapolated to what happens with treatment. In every study, treatment with estrogen decreases breast cancer risk. Observation at baseline does not prove causation. The most recent issue of JAMA proved that the only drug to decrease breast cancer mortality was estrogen! It was not a SERM or AI.
Meta-Analyses of the Risks, Benefits, Complications, Adverse events, and Outcomes Associated with Testosterone Replacement
One would think that the cardiovascular and endocrine worlds would embrace this as a gamechanger for preventing both diabetes and CVD.
Although not all hormones are created equal, you may find that when speaking to your doctor about hormone therapy, the names are used interchangeably and without regard for source or structure. That’s why it’s important for you to know the disparities in hormonal therapy and how those variations can make a huge difference in how you feel and your overall, long-term health.
Every occupation has its occupational hazards.
Nurses get stuck with needles. Police officers and military personnel get shot with real bullets in the line of duty. Firefighters get burned and suffer from smoke inhalation.
In 1860, Orange, New Jersey physician J. Addison Freeman published an article in The Transactions of the Medical Society of New Jersey entitled “Mercurial Disease Among Hatters.” (1) Dr. Freeman gave a clinical account of symptoms common among people who worked in the hat-making industry. This occupational hazard earned affected hat makers the term “Mad Hatter” for the psychological and neurological symptoms of erethism or mercury poisoning. (18)
What if we discovered that members of a specific occupation group had high rates of depression, physical and emotional exhaustion, depersonalization, and lack of a sense of personal accomplishment?