Insulin Resistance and Alzheimer’s Dementia
Insulin Resistance and Alzheimer's Dementia by: Neal Rouzier, MD At Hormones and Beyond 2020, I addressed the effect that Insulin Resistance had on the risk and progression of cancer. Last
LDL Cholesterol: Is It Responsible for CVD and are Statins the Solution?
LDL Cholesterol: Is It Responsible for CVD and are Statins the Solution? by Krista Russ Statins have long been the gold standard for treating high cholesterol since 1987, over thirty
How to Protect Against Collateral Damage
We continue to prescribe medicines that make IR, DM, CVD, and cancer worse, but we ignore the harm due to the therapeutic illusion that the benefits outweigh the risks. Yet we continue to ignore the plethora of data and studies demonstrating how to avoid these risks and protect against DM, CVD, and cancer.
PCSK-9 Inhibitors : Another Therapeutic Illusion
Recently, a new cholesterol lowering drug was approved in the U.K. The press-release heralded Inclisiran, simply another PCSK-9 inhibitor, to be a game changer as it will save thousands of lives by lowering cholesterol. No, there are no outcome studies yet, only studies that demonstrate it lowers serum cholesterol 50% more than statins alone. The authors assume and extrapolate that lowering LDL cholesterol with this drug will result in thousands of lives saved. That is termed therapeutic illusion.
The CVD and Cancer Insanity Cycle: What Should we do if What we are Doing Isn’t Working?
As clinicians we try to be problem solvers. It is part of our training, try to figure out what’s wrong, and then to fix it. Problem solved. However, what should we do if what we are doing isn’t working? Keep doing the same thing? What if the patient does not get better? What if the patient doesn’t feel better? What if the incidence of CVD continues to increase despite all the medications we prescribe? What if the incidence of cancer continues to increase even though cancer treatments themselves once you get cancer have improved? It is often said that insanity is doing the same experiment over and over again expecting to see and hoping to see different results.